About me

Hi, I’m Quilee Simeon, a research engineer trained at MIT working at the intersection of machine learning, neuroscience, and scientific computing. I’m currently work part-time with MIT’s Office of Research Computing and Data, and hold an M.S. in Computational Neuroscience and a B.S. in Computation and Cognition from MIT.

🧠 Research Focus

My work centers on multimodal neural data modeling as a platform for understanding how biological neural systems process information. I integrate data across neural dynamics, connectomics, and transcriptomics using machine learning frameworks including transformer architectures and self-supervised learning.

Key Research Areas:

  • Multimodal neural data integration and modeling
  • Self-supervised learning for neural systems
  • Transformer architectures for time-series neural activity
  • Graph-based learning approaches for connectome data
  • Neural efficiency and interpretability

πŸ’Ό Professional Experience

MIT Office of Research Computing and Data β€” Research Computing Technical Staff (Nov 2025 – Present)

Numenta, Inc. β€” Machine Learning Research Intern (June 2025 – September 2025)

  • Developed distillation methods for transferring sparsity patterns from large to small models
  • Designed sparse weight and activation mechanisms for efficient inference
  • Contributed to external collaboration on LLM inference optimization

MIT Department of Brain and Cognitive Sciences β€” Graduate Researcher (2022 – 2025)

  • Built large-scale data pipelines for multimodal neural datasets
  • Modeled neural population dynamics using graph-based architectures
  • Integrated transcriptomic and anatomical data for neuron identity prediction

πŸ› οΈ Technical Expertise

Machine Learning & AI: Transformer models, contrastive learning, spectral normalization, diffusion models, reinforcement learning, neural network interpretability

Scientific Computing: Python, PyTorch, Julia, high-performance cluster computing (SLURM-based systems)

Data Engineering: Neural data preprocessing, signal aggregation, connectome-based modeling

Software Tools: NumPy, PyTorch Geometric, OpenAI API, Hugging Face Datasets, Matplotlib, Marimo/Pluto notebooks

🎯 Current Direction

I’m transitioning toward applied ML and AI systems roles that blend algorithmic research with scientific applications. I’m particularly interested in:

  • Building generalizable models that bridge biological and artificial intelligence
  • Working in collaborative environments that value both research depth and practical engineering
  • Expanding expertise in reinforcement learning, generative modeling, and distributed systems

I’m open to Research Engineer, Applied Scientist, or ML Systems positions.

πŸ… Leadership & Community

  • Co-President, IEEE-HKN (Eta Kappa Nu) Honor Society β€” MIT Chapter
  • MIT Black Student Union β€” Social Chair
  • Secretary, Beta Chapter of Theta Chi at MIT
  • Mentor and advocate for open science, data transparency, and interdisciplinary education
  • Strong commitment to supporting underrepresented minorities in STEM

🌍 Background

I grew up in St. Lucia and completed my B.S. in Computation and Cognition (minor in Statistics & Data Science) and an M.S. in Computational Neuroscience at MIT. Outside of research, I enjoy reading fiction, hiking, and traveling to understand different cultures.


β€œI’m driven by the idea that understanding intelligence β€” biological or artificial β€” means learning how information transforms meaningfully through systems.”